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About the CellCognition Project

by held last modified May 13, 2018 12:59 PM


Who is CellCognition?



Former developers and contributors

  • Michael Held - project initiator
  • Bernd Fischer - contributor
  • Christoph Sommer - developer
  • Höfler Rudolf - developer


Work in the Gerlich laboratory is supported by Swiss National Science Foundation (SNF) research grant 3100A0-114120, SNF ProDoc grant PDFMP3_124904, a European Young Investigator (EURYI) award of the European Science Foundation, an EMBO YIP fellowship, and a MBL Summer Research Fellowship, an ETH TH grant, a grant by the UBS foundation, a Roche Ph.D. fellowship, and a Mueller fellowship of the Molecular Life Sciences Ph.D. program Zurich.

Work in the Ellenberg laboratory is supported by a European Commission grant within the Mitocheck consortium (LSHG-CT-2004-503464).

Bernd Fischer was supported by European Commission’s seventh framework program project Cancer Pathways.


Held M, Schmitz MHA, Fischer B, Walter T, Neumann B, Olma MH, Peter M, Ellenberg J, and Gerlich DW.
CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.
Nature Methods (2010) Sep;7(9):747-54. Epub 2010 Aug 8. - PubMed

Schmitz MHA, Held M, Janssens V, Hutchins JR, Hudecz O, Ivanova E, Goris J, Trinkle-Mulcahy L, Lamond AI, Poser I, Hyman AA, Mechtler K, Peters JM, and Gerlich DW.
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.
Nature Cell Biology (2010) Sep;12(9):886-93. Epub 2010 Aug 15. - PubMed

Piwko W, Olma MH, Held M, Bianco JN, Pedrioli PG, Hofmann K, Pasero P, Gerlich DW, Peter M.
RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells.
EMBO Journal (2010) Nov 26. - PubMed

Wurzenberger C, Held M, Lampson MA, Poser I, Hyman AA, Gerlich DW.
Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores.
Journal of Cell Biology (2012) Jul 23;198(2):173-83. Epub 2012 Jul 16. PubMed

Mall M, Walter T, Gorjánácz M, Davidson IF, Nga Ly-Hartig TB, Ellenberg J, Mattaj IW.
Mitotic lamin disassembly is triggered by lipid-mediated signaling.
Journal of Cell Biology (2012) Sep 17;198(6):981-90. PubMed

Zhong Q, Busetto AG, Fededa JP, Buhmann JM, Gerlich DW.
Unsupervised modeling of cell morphology dynamics for time-lapse microscopy.
Nature Methods (2012) May 27;9(7):711-3. PubMed

Sommer C, Held M, Fischer B, Huber W, Gerlich DW.
CellH5: a format for data exchange in high-content screening.
Bioinformatics (2013) Jun 15;29(12):1580-2. doi: Epub 2013 Apr 16. PubMed


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