About the CellCognition Project
Who is CellCognition?
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Daniel Gerlich - project leader Senior scientist at IMBA Vienna and interested in the understanding of molecular mechanisms underlying the cell division machinery as well as methods for automated cell phenotyping based on supervised and unsupervised machine learning. |
| Christoph Langer - developer |
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Thomas Walter - developer Researcher at the Institut Curie Paris (formerly at EMBL Heidelberg) with focus on biological image analysis. |
Former developers and contributors
- Michael Held - project initiator
- Bernd Fischer - contributor
- Christoph Sommer - developer
- Höfler Rudolf - developer
Funding
Work in the Gerlich laboratory is supported by Swiss National Science Foundation (SNF) research grant 3100A0-114120, SNF ProDoc grant PDFMP3_124904, a European Young Investigator (EURYI) award of the European Science Foundation, an EMBO YIP fellowship, and a MBL Summer Research Fellowship, an ETH TH grant, a grant by the UBS foundation, a Roche Ph.D. fellowship, and a Mueller fellowship of the Molecular Life Sciences Ph.D. program Zurich.
Work in the Ellenberg laboratory is supported by a European Commission grant within the Mitocheck consortium (LSHG-CT-2004-503464).
Bernd Fischer was supported by European Commission’s seventh framework program project Cancer Pathways.
Publications
Held M, Schmitz MHA, Fischer B, Walter T, Neumann B, Olma
MH, Peter M, Ellenberg J, and Gerlich DW.
CellCognition: time-resolved phenotype annotation in high-throughput
live cell imaging.
Nature Methods (2010) Sep;7(9):747-54. Epub 2010 Aug 8. - PubMed
Schmitz MHA, Held M, Janssens V, Hutchins JR, Hudecz O, Ivanova E, Goris J, Trinkle-Mulcahy L, Lamond AI, Poser I, Hyman AA, Mechtler K, Peters JM, and Gerlich DW.
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.
Nature Cell Biology (2010) Sep;12(9):886-93. Epub 2010 Aug 15. - PubMed
Piwko W, Olma MH, Held M, Bianco JN, Pedrioli PG, Hofmann K, Pasero P, Gerlich DW, Peter M.
RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells.
EMBO Journal (2010) Nov 26. - PubMed
Wurzenberger C, Held M, Lampson MA, Poser I, Hyman AA, Gerlich DW.
Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores.
Journal of Cell Biology (2012) Jul 23;198(2):173-83. Epub 2012 Jul 16. PubMed
Mall M, Walter T, Gorjánácz M, Davidson IF, Nga Ly-Hartig TB, Ellenberg J, Mattaj IW.
Mitotic lamin disassembly is triggered by lipid-mediated signaling.
Journal of Cell Biology (2012) Sep 17;198(6):981-90. PubMed
Zhong Q, Busetto AG, Fededa JP, Buhmann JM, Gerlich DW.
Unsupervised modeling of cell morphology dynamics for time-lapse microscopy.
Nature Methods (2012) May 27;9(7):711-3. PubMed
Sommer C, Held M, Fischer B, Huber W, Gerlich DW.
CellH5: a format for data exchange in high-content screening.
Bioinformatics (2013) Jun 15;29(12):1580-2. doi: Epub 2013 Apr 16. PubMed
